[A case of acute respiratory distress syndrome induced by inhalation of hydrogen chloride].

Poisoning induced by inhalation of hydrogen chloride has significant effects on the respiratory system. It can cause severe pulmonary edema and acute respiratory distress syndrome (ARDS) in the early stage, and even death in critical cases. As a novel treatment for ARDS, the efficacy of sivelestat sodium in infection-induced ARDS has been widely verified, but its application in ARDS caused by chemical poisoning is still scarce in literature. Here we report a case of ARDS induced by hydrogen chloride inhalation which was successfully treated with sivelestat sodium and conventional treatment.

Experimental study of perturbative particle transport in the HL-2A tokamak.

Perturbative particle transport experiment has been performed in the HL-2A tokamak by using supersonic molecular beam injection (SMBI) as an external particle source. The spatiotemporal evolution of edge density perturbation is traced and the particle source and the flux-gradient relation are obtained experimentally. The flux-gradient relation is found to be far from the diffusive model and three different transport processes are revealed, including pinch-dominant process, diffusion-pinch process and intermittent decays.

[Impact of antifungal therapy in mechanically ventilated patients with Candida spp. colonization in lower respiratory tract].

Objective: To explore the impact of antifungal therapy in mechanically ventilated patients with Candida spp. colonization in lower respiratory tract. Methods: In this retrospective study, patients required mechanical ventilation with pulmonary Candida spp. colonization admitted into the intensive care unit (ICU) between July 2012 and June 2016 were included. The patients were divided into the treatment group and control group according to whether or not they received antifungal therapy. The isolation rate of multidrug-resistant (MDR) bacteria, the incidence of ventilator-associated pneumonia (VAP), duration of mechanical ventilation, length of ICU stay, total length of hospital stay, the 28-day mortality and the overall mortality were compared between the two groups. Results: Totally, 101 patients were studied. The number of cases in treatment group was 56 and the control group was 45. The treatment group had a lower incidence of MDR bacteria isolation rate and VAP compared with the control group (16.1% vs 33.3%, 5.4% vs 17.8% respectively, both P<0.05). There were significant differences in the duration of mechanical ventilation [(17.3±5.7) days vs (22.5±7.2) days, P<0.05], length of ICU stay [(23.3±5.6) days vs (28.7 ±4.8) days, P<0.05] and the average length of hospital stay [(36.2±8.7) days vs (43.6±9.0) days, P<0.05)] in the treatment group compared with the control group. There were no statistical difference between the two groups in the 28-day mortality and the overall mortality. Conclusion: Treatment of respiratory Candida spp. colonization in mechanically ventilated patients may reduce isolation rate of MDR bacteria, the incidence of VAP, duration of mechanical ventilation, length of ICU stay and total length of hospital stay.

[Factors associated with malnutrition among infants and young children aged 6-23 months in poor rural areas in Hunan Province, China].

Objective: To describe the situation and identify factors associated with malnutrition among infants and young children aged 6-23 months in poor rural areas in Hunan Province in 2015. Methods: 8 735 rural infants and young children aged 6-23 months in 30 poor counties of Wuling Mountains and Luoxiao Mountains in Hu'nan province were selected by township-level probability proportional to size sampling (PPS) in August 2015, infants' body length and weight were measured, and questionnaires were used to collect infants' information on personal and family, and feeding status in the past 24 h. The prevalence of stunting, underweight and wasting were calculated according to the Growth Standards of Child Aged Under 7 in China which was established in 2009 by Community Health Department of National Health and Family Planning Commission, China (formerly Chinese MOH), and the prevalence of malnutrition was calculated according to the classification of children with anthropometric failure. Multi non-conditional logistic regression model were used to analyze factors associated with malnutrition among infants and young children aged 6-23 months. Results: The prevalence of malnutrition among infants and young children aged 6-23 months was 13.7% (1 198/8 735), the prevalence of stunting, underweight and wasting among infants and young children aged 6-23 months were 4.8% (419/8 735), 9.7% (849/8 735) and 6.1% (531/8 735) respectively. Compared with male group, the OR value of malnutrition for the female group was 1.16; Compared with Han ethnic group, the OR value of malnutrition for the Miao and Tujia ethnic group were 0.83 and 0.66, respectively; Compared with mother with an education level of primary school or below, the OR value of malnutrition for the mother with junior high school, senior high school and university or above education were 0.65, 0.61 and 0.56, respectively; Compared with father with an education level of primary school or below, the OR value of malnutrition for the father with senior high school and university or above education were 0.71 and 0.61 respectively; Compared with normal birth weight group, the OR value of malnutrition for the low birth weight group and high birth weight group were 2.85 and 0.27 respectively; Compared with normal delivery group, the OR value of malnutrition for the premature delivery group was 1.37; all P values<0.05. Conclusion: The prevalence of malnutrition among infants and young children aged 6-23 months in poor rural areas in Hunan province in 2015 was high; Infants and young children who were female, Han ethnic, parents with low education, low birth weight and premature delivery had higher risk of malnutrition.

[Status of, and factors associated with, complementary feeding among infants and young children aged 6- 23 months in poor rural areas of Hunan Province, China].

Objective: To describe the status of, and to identify the factors associated with, complementary feeding among infants and young children aged 6- 23 months in poor rural areas of Hunan Province, China. Methods: A total of 8 735 infants and young children aged 6- 23 months from 30 poor rural counties in the Wuling and Luoxiao Mountains in Hunan Province were selected by township-level probability-proportional-to-size sampling in August 2015. Questionnaires were used to collect information on the feeding status of the infants in the previous 24 hours, along with personal/family information. The qualified rate of minimum dietary diversity (MDD), the minimum meal frequency (MMF) and the minimum acceptable diet (MAD) were calculated according to the WHO indicators for assessing infant and young child feeding practices. Multi non-conditional logistic regression models were used to analyze factors associated with complementary feeding among infants and young children aged 6- 23 months. Results: The findings indicated that 73.9% (6 452/8 735) of infants and young children aged 6-23 months received the minimum dietary diversity, 81.6% (7 124/8 735) of infants and young children aged 6- 23 months received the minimum meal frequency and 49.0% (4 276/8 735) of infants and young children aged 6- 23 months received an acceptable diet. Compared with the boys, the OR for the MMF and MAD for the girls were 1.15 and 1.11, respectively. Compared with the 6-11 month group, the OR for the MDD for the 12-17 month and 18-23 month groups were 0.41 and 0.38, respectively; the OR for the MMF for the 12-17 month and 18-23 month groups were 1.53 and 2.46, respectively; and the OR for the MAD for the 12-17 month and 18-23 month groups were 0.60 and 0.60, respectively. Compared with the Han ethnic group, the OR for the MDD, MMF and MAD for the Miao ethnic group were 1.43, 1.72 and 1.56, respectively; for the Tujia ethnic group were 2.21, 2.02 and 2.11, respectively; and for the Dong ethnic group were 0.62, 0.61 and 0.64, respectively. When analyzing data related to the children's mothers, compared with women who gestated at the age of 25- 29, the OR for the MMF for women who gestated at less than 20 years of age was 1.59 and at greater than or equal to 35 years of age was 1.33. Compared with women with primary school education or below, the OR for the MDD, MMF and MAD for women with junior high school education were 0.77, 0.74 and 0.80, respectively; for women with senior high school education were 0.67, 0.65 and 0.68, respectively; and for women educated to university level or above were 0.66, 0.47 and 0.60, respectively. Compared with the normal birth weight group, the OR for the MMF for the low birth weight group was 0.71, and for the high birth weight group was 1.30. Compared with the caregivers who provided qualified feeding knowledge, the OR for the MDD, MMF and MAD for the caregivers who provided unqualified feeding knowledge were 1.45, 1.30 and 1.40, respectively. Compared with the breastfed group, the OR for the MDD and the MMF for the non-breastfed group were 0.53 and 0.36, respectively. All P values were <0.05. Conclusion: Most infants and young children aged 6-23 months in poor rural areas of China met the MDD and MMF requirements, but fewer met the MAD requirements. The risk factors in infants and young children for complementary feeding included being of female gender, lower in age (months), of Miao or Tujia ethnicity, being born to a mother who gestated at less than 20 or ≥35 years of age, being born to a mother of low education, having a high birth weight, having a caregiver who provided unqualified feeding knowledge and being breastfed.

The supersonic molecular beam injector as a reliable tool for plasma fueling and physics experiment on HL-2A.

On HL-2A tokamak, supersonic molecular beam injection (SMBI) has been developed as a routine refueling method. The key components of the system are an electromagnetic valve and a conic nozzle. The valve and conic nozzle are assembled to compose the simplified Laval nozzle for generating the pulsed beam. The appurtenance of the system includes the cooling system serving the cooled SMBI generation and the in situ calibration component for quantitative injection. Compared with the conventional gas puffing, the SMBI features prompt response and larger fueling flux. These merits devote the SMBI a good fueling method, an excellent plasma density feedback control tool, and an edge localized mode mitigation resource.

Diamagnetic measurements by concentric loops in the HL-2A tokamak.

The diamagnetic concentric loop method in the HL-2A tokamak is described in this article. The system consists of two concentric poloidal loops with different areas enclosing the plasma column and a short time constant differential integrator, RC < 1 ms. The diamagnetic flux in HL-2A ranges from 1 mWb to 2 mWb for typical discharges with plasma current Ip = 100-400 kA. The integrator output ranges from 0.1 V to 0.2 V with time constant RC = 0.5 ms, and differential area ΔS∕Sout ≈ 7%. Using hybrid analog-digital compensation, the integration drift can be well compensated within 5 mV∕10 s, which can meet the requirement of the concentric loop system. In this method, the measurement of differential area ΔS is not required. The vacuum toroidal flux can be compensated by adjusting the resistance in the integration circuit for several discharges with toroidal field only, which minimizes the additional error produced by a measurement of differential area. The diamagnetic concentric loop system improved the signal to noise ratio by using the short time constant integration. The system with a resolution of ±0.2 kJ can be used to study rapid changes in plasma stored energy, such as the additional power absorbed by the plasma, and the energy loss caused by edge localized modes.

Observation of a spontaneous particle-transport barrier in the HL-2A tokamak.

Using the profile analysis, the density perturbation transport analysis, and the Doppler reflectometry measurement, for the first time a spontaneous and steady-state particle-transport barrier has been evidenced in the Ohmic plasmas in the HL-2A tokamak with no externally applied momentum or particle input except the gas puffing. A threshold in density has been found for the observation of the barrier. The particle diffusivity is well-like, and the convection is found to be inward outside the well and outward inside the well. The formation of the barrier coincides with the transition between the trapped electron mode and the ion temperature gradient driven mode.

A method of particle transport study using supersonic molecular beam injection and microwave reflectometry on HL-2A tokamak.

A method of the particle transport study using supersonic molecular beam injection (SMBI) and microwave reflectometry is reported in this paper. Experimental results confirm that pulsed SMBI is a good perturbation source with deeper penetration and better localization than the standard gas puffing. The local density modulation is induced using the pulsed SMBI and the perturbation density is measured by the microwave reflectometry. Using Fourier transform analysis for the local density perturbation, radial profiles of the amplitude and phase of the density modulation can be obtained. The experimental results in HL-2A show that the particle injected by SMBI is located at about r/a=0.65-0.75. The position of the main particle source can be determined through three aspects: the minimum of the phase of the first harmonic of the Fourier transform of the modulated density measured by microwave reflectometry; the H(a) intensity profile and the local density increase ratio. The maximum of the amplitude of the first harmonic shifts often inward relative to the particle source location, which indicates clearly there is an inward particle pinch in this area. Good agreement has been found between the experimental results and the simulation using analytical transport model. The particle diffusivity D and the particle convection velocity V have been obtained by doing this simulation. The sensitivity in the transport coefficients of the amplitude and the phase of the density modulation has been discussed.

ß-induced Alfvén eigenmodes destabilized by energetic electrons in a Tokamak plasma.

The ß-induced Alfvén eigenmode (BAE) excited by energetic electrons has been identified for the first time both in the Ohmic and electron cyclotron resonance heating plasma in HL-2A. The features of the instability, including its frequency, mode number, and propagation direction, can be observed by magnetic pickup probes. The mode frequency is comparable to that of the continuum accumulation point of the lowest frequency gap induced by the shear Alfvén continuous spectrum due to finite ß effect, and it is proportional to Alfvén velocity at thermal ion ß held constant. The experimental results show that the BAE is related not only with the population of the energetic electrons, but also their energy and pitch angles. The results indicate that the barely circulating and deeply trapped electrons play an important role in the mode excitation.